Courage, Muriel, and Eustace win a trip to an art museum in Europe. Muriel talks about how her mother always said that Muriel always looked liked the Mona Lisa. They go into the museum right before closing time, and then get locked in. They fall asleep in there and when they wake up, Muriel walks up to the painting of the Mona Lisa and gets pulled in. Then the Mona Lisa steps out of the painting (the planets align and the portrait people switch places with real people). Eustace switches places with The Thinker and Courage has to chase down the Mona Lisa so he can get Muriel back. The Thinker and the Mona Lisa go on a date into some portraits. Courage and Muriel enter a painting of what they say looks like their house (and it is), and they sit there at home wondering where Eustace is.
- This is the first episode where Arthur Anderson voices Eustace.
- This episode features Edward Hopper's Nighthawks, Grant Wood's American Gothic and Auguste Rodin's The Kiss as part of the plot
- The concept of this episode is a bit similar to the classic Nintendo 64 video game Super Mario 64.
- On the titlecard there are two different titles; the large title says "So in Louvre are we two", however directly below that is a smaller title which states "So In Louvre, We Are Two". It is also notable that every word in the latter is capitalized, while the former only capitalizes the first letter and proper nouns (the Louvre).